Nicolas A. Karakatsanis, PhD, DABSNM
Assistant Professor of Biomedical Engineering
Weill Cornell Medical College | Cornell University
E-mail: nak2032 [at] med [dot] cornell [dot] edu
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Dr. Nikolaos (Nicolas) A. Karakatsanis is currently (Sep. 2017 – now) an Assistant Professor of Biomedical Engineering in the Radiology Department of Weill Cornell Medical College, Cornell University in New York, NY, USA. Dr Karakatsanis is also certified from the American Board of Science in Nuclear Medicine (ABSNM) with a specialty in Nuclear Medicine Physics and Instrumentation. Nicolas is also a Senior IEEE member and the appointed executive Secretary official (2-year term, 2021-2022) in the Nuclear Medical Imaging Sciences Council (NMISC) of the IEEE Nuclear and Plasma Sciences Society (NPSS). Previously, Nicolas had served as board member (3-year term, 2017-2019) of NMISC, elected from the IEEE NPSS members. Moreover, Nicolas is currently elected as the executive Secretary official (2-year term, 2019-2021) of the Physics, Instrumentation and Data Sciences Council (PIDSC) from the members of the Society of Nuclear Medicine and Molecular Imaging (SNMMI). Prior to that, he had been appointed as the intern of PIDSC earning a 2-year scholarship (2017-2019) which allowed him to create the NMMItools website hosting an up-to-date organized collection of online reference resources to active software and data repositories related to Nuclear Medicine and Molecular Imaging research and quality assurance tasks. Nicolas is also serving as Associate Editor in the Clinical Imaging journal and the Nuclear Medicine subsection of the Frontiers in Medicine journal.
Nicolas is aiming to enhance the diagnostic, prognostic and theranostic value of pre-clinical and clinical Positron Emission Tomography (PET) imaging for cardiovascular, oncologic and neurologic diseases. His main research focus has been the development of clinically feasible and quantitative PET/CT and PET/MR imaging methodologies, using:
- PET/CT and simultaneous PET/MR clinical systems
- novel and clinically adoptable whole-body dynamic PET acquisition protocols
- multi-parametric, dynamic and dual-tracer PET/MR imaging methods with a focus on translational imaging of cardiovascular diseases molecular activity
- whole-body PET tracers kinetic modeling analysis coupled with robust kinetic parameter estimation techniques at the image voxel level
- advanced 4D parametric PET/CT and PET/MR image reconstruction for enhanced molecular imaging quantification
- cost-effective long axial field-of-view PET scanners with adaptable sparse detector configurations
- dual-tracer cardiovascular PET/MR image acquisition methods for synergistic evaluation of different molecular pathways of atherosclerosis
- PET-driven bone segmentation for enhanced PET image quantification in simultaneous PET/MR imaging
- List mode data-driven respiratory and cardiac motion estimation and correction techniques within and after PET image reconstruction
- synergistic PET/MR image reconstruction for partial volume error (PVE) correction
- evaluation of Time-of-Flight (TOF), Continuous Bed Motion (CBM) and Resolution Modeling (PSF) technologies clinical benefit in specific PET/CT & PET/MR protocols
- Noise Equivalent Count Rate (NECR)-based optimization of administered PET radiotracer dosage in the clinic
Dr Karakatsanis is also appointed as Adjunct Assistant Professor at the Biomedical Engineering and Imaging Institute (BMEII), formally the Translational and Molecular Imaging Institute (TMII), at the Icahn School of Medicine at Mount Sinai, New York, NY, USA, since the beginning of 2018, leading a number of projects in dual-tracer and dynamic cardiovascular PET/MR imaging as a member of the Cardiovascular Imaging Lab led by the Director of the BMEII, Prof. Zahi Fayad. Previously Nicolas had joined BMEII as a senior PET/MR and PET/CT research scientist (July 2015 – Sep 2017).
Between January 2014 and July 2015, Nicolas had received training as a Postdoctoral Research Associate at Geneva University Hospital (Hôpitaux Universitaires de Genève, HUG) after joining the PET Instrumentation and Neuroimaging laboratory (PINlab) led by Dr. Habib Zaidi, honorary professor also at the University Medical Center of Groningen (UMCG) in Netherlands.
Dr Karakatsanis also maintains an active and close collaboration with the Quantitative Tomography Lab led by Dr Arman Rahmim, currently Associate Professor of Radiology and Physics at University of British Columbia, Canada. In the past, Nicolas had been appointed at Johns Hopkins University Hospital as a Postdoctoral Research Fellow and trainee Medical Physicist (Feb 2011 – Dec 2013) under the supervision of Prof. Rahmim.
Furthermore, Nicolas is working closely with Dr Konstantina S. Nikita, Professor at the School of Electrical and Computer Engineering and head of the Biomedical Simulations and Imaging (BIOSIM) Laboratory at the National Technical University of Athens (NTUA), Greece, and Dr. George Loudos, Assistant Professor at the Biomedical Engineering Department of the University of Western Attica, Greece.
Nikolaos (Nicolas) A. Karakatsanis, PhD, DABSNM
Assistant Professor of Biomedical Engineering in Radiology
Division of Radiopharmaceutical Sciences | Department of Radiology
Weill Cornell Medical College | Cornell University
515 East 71st St., 1st Floor, S-114, New York, NY, 10021, USA
Adjunct Assistant Professor
BioMedical Engineering and Imaging Institute | Department of Radiology
Icahn School of Medicine at Mount Sinai | Mount Sinai Medical Center
1470 Madison Ave, 1st Floor, TMII, New York, NY, 10029, USA